The Purpose of Sermorelin Acetate Therapy
Sermorelin Acetate Therapy aims to cause the pituitary gland to increase growth hormone production in humans.
Adult Sermorelin, growth hormone therapy, is to reverse the effects of aging and secure the extensive treatment benefits described below.
What is Sermorelin Acetate GH-RH?
Sermorelin Acetate is a “growth hormone-releasing hormone” (GHRH). This prescription drug is compounded by U.S. pharmacies under a physician’s prescription and is patient-self-injected subcutaneously.
It stimulates the pituitary gland to produce increased amounts of human growth hormone naturally.
Sermorelin Acetate is a truncated analog of a growth hormone-releasing factor (GRF 1-44) that is naturally produced by the brain to stimulate pituitary production of human growth hormone.
The increased volume of human growth hormone (hGH) produced by the pituitary gland causes the liver to produce more Insulin-Like Growth Factor-1 (IGF-1), which results in the benefits of treatment provided to the adult patient.
Benefits of Sermorelin Acetate Growth Hormone Releasing Hormone Therapy
- Increases the development of lean body mass through the development of new muscle cells
- Reduces body fat through lipolysis
- Increases energy and vitality
- Increases strength
- Increases endurance
- Accelerates healing from wounds or surgery
- Strengthens the heart
- Enhances the immune system
- Increases IGF-1 production
- Improves sleep quality
- Increases calcium retention and strengthens and increases the mineralization of bone or bone density.
- Increases protein synthesis and stimulates the growth of all internal organs except the brain.
- Plays a role in fuel homeostasis.
- Reduces liver uptake of glucose, an effect that opposes that of insulin.
- Promotes liver glucogenesis.
- Contributes to the maintenance and function of pancreatic islets.
Sermorelin Growth Hormone (GHRH) Therapy
As a result of Sermorelin Growth Hormone (GHRH) Therapy, the liver converts the increased volume of human growth hormone secreted by the stimulated pituitary gland into IGF-1.
The increased amount of IGF-1 in the bloodstream increases the metabolism and growth of new cells within the body’s organs and bones.
This treatment is prescribed for unlabeled use in adults to reverse the effects of aging, increase bone density, enhance the immune system, and strengthen the heart and other organs.
Since the increased volume of human growth hormone is produced by the body’s pituitary gland, the body’s endocrine system will not allow more growth hormone to be produced by the Sermorelin GH-RH stimulation of the pituitary than the body can safely process within the endocrine self-monitoring system.
Growth Hormone-Releasing Hormone (Sermorelin Acetate) has been specifically approved for medical use in increasing growth hormone levels in children deficient in growth hormone production.
Its use to increase the growth hormone and IGF-1 levels in adults is an off-label use of this prescription drug and not the approved use. It is specifically approved only for use in children and was formerly manufactured under the prescription drug brand name of Geref.
Growth Hormone-Releasing Hormone (Sermorelin Acetate) Therapy causes the pituitary gland to increase human growth hormone and IGF-1 levels.
It is a prescription drug that may be prescribed for adults for unlabeled uses, and the cost is about one-third the price of illegal adult synthetic, recombinant human growth hormone (HGH) injection therapy.
Growth Hormone-Releasing Hormone (Sermorelin Acetate) Therapy
Sermorelin Acetate Therapy for adults increases lean muscle mass, reduces body fat, and counteracts aging effects. It stimulates the pituitary gland to produce more human growth hormone, increasing IGF-1 production by the liver.
Advantages of Sermorelin (GH-RH) over Synthetic HGH
- Legal Status: It’s legal to prescribe Sermorelin for off-label use in adults. In contrast, it’s a federal crime to prescribe synthetic HGH (somatropin) to adults unless they have a diagnosed pituitary disease or AIDS-related muscle wasting.
- Cost: Sermorelin therapy costs about 1/3 of the price of synthetic HGH treatments.
- Safety: Sermorelin is safer because it works with the body’s natural systems. The endocrine system regulates production, preventing excessive growth hormone levels. This avoids the risk of uneven organ growth associated with synthetic HGH.
Legal Information
The U.S. Drug Enforcement Agency enforces laws against illegal HGH distribution. Many healthcare professionals have faced felony charges for distributing HGH for unapproved purposes like anti-aging or medical rejuvenation.
For more information on illegal online prescriptions, visit:
The relevant federal statute is US Code Annotated, Title 21 Food and Drugs, Chapter 3, Subchapter III, Section 333. (e) (1).
Important Notes
- Possessing illegally prescribed recombinant growth hormone is a criminal offense for patients.
- Sermorelin can be legally prescribed for unlabeled use in adults with growth hormone deficiency.
- The Secretary of Health and Human Services must approve any use of synthetic HGH in adults outside of the specified exceptions.
